Building new drugs just got easier

A method for modifying organic molecules has been developed that significantly expands the possibilities for developing new pharmaceuticals and improving old ones. The innovation makes it easier to modify existing organic compounds by attaching biologically active “functional group” to drug molecules. A typical small-molecule drug derives its activity from such functional groups, which are bound to a relatively simple backbone structure consisting chiefly of carbon atoms.
Journal Reference:

  1. Ri-Yuan Tang, Gang Li, Jin-Quan Yu. Conformation-induced remote meta-C–H activation of aminesNature, 2014; 507 (7491): 215 DOI: 10.1038/nature12963

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